Acute Toxicity and Pharmacokinetics

Bioavailability and acute toxicology evaluation are critical components of early preclinical drug development. Piedmont Research Center offers basic services in bioavailability, pharmacokinetics and toxicity analysis. All studies are conducted in the spirit of GLP. GLP toxicology studies are available onsite through collaboration with Biotechnics, Inc.

Toxicology studies can include any or all of the following:

• Timed dosing and sampling
• Tissue and/or organ preservation
• Plasma and/or serum sampling
• Radiolabeled compounds
• Histology and pathology
• CBC with differentials
• Chem CS
• GLP monitoring

Pharmacokinetic sampling can be designed as a stand alone one- to thirty-day study, or it can be incorporated into your efficacy protocol.