Studies Continue for a New Drug-Conjugation Technology
Three studies were contracted over the course of two years for testing a
novel drug-conjugation technology. All three tests failed to show efficacy
and demanded extensive customization and technical proficiency.
Recently, a fourth conjugate showed promising anti-tumor activity. Efforts
are under way to determine the optimal dose and schedule, determine PK parameters
and toxicity profiles and profile activity of the agent against a variety
of tumor models.