Horacio Plotkin, M.D., F.A.A.P.

Plotkin, Horacio

Vice President
Medical Lead
Rare Disease and Pediatric Center of Excellence

Horacio Plotkin, M.D., F.A.A.P., is vice president and therapeutic area head for pediatrics and rare diseases. In this role, Dr. Plotkin is a key member of PPD’s Rare Disease and Pediatric Center of Excellence. The center addresses strategic, operational, medical and scientific challenges presented by pediatric studies and small, widely dispersed patient populations affected by rare diseases. Additionally, he provides clinical trial design guidance to clients in these therapeutic areas.


Dr. Plotkin has extensive clinical experience, including as the founder and medical director of the pediatric metabolic bone diseases program at Children’s Hospital in Omaha, Nebraska. He was an adjunct associate professor of pediatrics and orthopedic surgery at the University of Nebraska School of Medicine. Dr. Plotkin previously held positions at Genzyme, Enobia Pharma, Alexion Pharmaceuticals, Inc., Retrophin Inc. and Shire.

Dr. Plotkin is a member of the scientific advisory board for several rare disease patient advocacy organizations. He has authored eight chapters in medical textbooks and more than 50 scientific papers, and he’s presented more than 70 abstracts in national and international scientific meetings.


Dr. Plotkin earned his medical degree from the University of Buenos Aires School of Medicine. He completed a residency program in pediatrics, followed by four fellowships: pediatric endocrinology (J. P. Garrahan Pediatric Hospital, Buenos Aires), metabolic bone diseases (Metabolic Research Institute, Buenos Aires), endocrinology (Yale University School of Medicine, New Haven) and pediatric metabolic bone diseases (Shriners Hospital for Children and Department of Surgery, McGill University, Montreal).

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